Table 1. Primer sequences for RT-qPCR.

Gene	Primer sequence
hsa_circ_0000515	F: 5′- GGTCAGACTGGGCAGGAGAT-3'
	R: 5′- GAGTGACAGGACGCACTCAG -3′
miR-326	F: 5′-CATCTGTCTGTTGGGCTGGA-3′
	R: 5′- AGGAAGGGCCCAGAGGCG-3′
ELK1	F: 5′- TCCCTGCTTCCTACGCATACA-3′
	R: 5′- GCTGCCACTGGATGGAAACT-3′
MMP-9	F: 5′- TGTACCGCTATGGTTACACTCG-3′
	R: 5′- GGCAGGGACAGTTGCTTCT-3′
TIMP-1	F: 5′- CTTCTGCAATTCCGACCTCGT-3′
	R: 5′- ACGCTGGTATAAGGTGGTCTG-3′
PCNA	F: 5′-GTAGTAAAGATGCCTTCTGGTG-3′
	R: 5′-TCTCTATGGTAACAGCTTCCTC-3′
Caspase3	F: 5′- CATGGAAGCGAATCAATGGACT-3′
	R: 5′- CTGTACCAGACCGAGATGTCA-3′
Beclin1	F: 5′- CCATGCAGGTGAGCTTCGT-3′
	R: 5′- GAATCTGCGAGAGACACCATC-3′
Caspase9	F: 5′- GAACTAACAGGCAAGCAGCAAA-3′
	R: 5′-ATCCTCCAGAACCAATGTCCAC-3′
p62	F: 5′-ACTGATGGCTGTAACGGTCTA-3′
	R: 5′- GGAAGCAGATGGCACAGAGG-3′
LC3	F: 5′-CATGAGCGAGTTGGTCAAGAT-3′
	R: 5′-TCGTCTTTCTCCTGCTCGTAG-3′
U6	F: 5′-CTCGCTTCGGCAGCACA-3′
	R: 5′-AACGCTTCACGAATTTGCGT-3′
GAPDH	F: 5′-TGGGTGTGAACCATGAGAAGT-3′
		R: 5′-TGAGTCCTTCCACGATACCAA-3′

Note: RT-qPCR, reverse transcription quantitative polymerase chain reaction; F, forward; R, reverse; miR-326, microRNA-326; ELK1, ETS transcription factor ELK1; MMP-9, matrix metallopeptidase 9; TIMP-1, TIMP metallopeptidase inhibitor 1; PCNA, proliferating cell nuclear antigen; LC3, light chain 3; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.