Table 1. Association of overall survival with clinicopathological characteristics in colorectal cancer patients.
| Characteristics | N | Univariate analysis | Multivariate analysis | ||||
| HR | 95% CI | P-value | HR | 95% CI | P-value | ||
| Ages (years) | 0.29 | 0.12 | |||||
| < 60 | 224 | 1.00 | 1.00 | ||||
| ≥ 60 | 315 | 1.33 | 0.78-2.26 | 1.35 | 0.82-1.93 | ||
| Gender | 0.77 | 0.89 | |||||
| Females | 184 | 1.00 | 1.00 | ||||
| Males | 355 | 1.08 | 0.64-1.83 | 1.01 | 0.56-1.74 | ||
| Location | 0.45 | 0.52 | |||||
| Left sided colon | 232 | 1.00 | 1.00 | ||||
| Right sided colon | 121 | 1.23 | 0.78-1.45 | 1.12 | 0.63-1.48 | ||
| Rectum | 186 | 0.89 | 0.65-1.23 | 0.92 | 0.55-1.28 | ||
| T stage | 0.02 | 0.02 | |||||
| T1/T2 | 87 | 1.00 | 1.00 | ||||
| T3/T4 | 452 | 2.32 | 1.86-2.66 | 2.02 | 1.52-2.42 | ||
| N stage | <0.01 | 0.05 | |||||
| N0 | 57 | 1.00 | 1.00 | ||||
| N1/N2 | 482 | 1.89 | 1.65-2.13 | 1.23 | 0.89-1.67 | ||
| Differentiation | <0.01 | 0.01 | |||||
| Low grade | 352 | 1.00 | 1.00 | ||||
| High grade | 187 | 2.01 | 1.45-2.23 | 1.62 | 1.48-1.92 | ||
| Microvascular involvement | <0.01 | 0.456 | |||||
| Absent | 100 | 1.00 | 1.00 | ||||
| Present | 439 | 1.44 | 1.12-1.65 | 1.21 | 0.68-1.41 | ||
| Peri-neural invasion | 0.08 | 0.06 | |||||
| Absent | 221 | 1.00 | 1.00 | ||||
| Present | 318 | 1.22 | 0.91-1.35 | 1.34 | 0.89-1.43 | ||
| Simultaneous Metastasectomy | <0.01 | <0.01 | |||||
| Performed | 181 | 1.00 | 1.00 | ||||
| Not performed | 358 | 2.45 | 1.66-2.89 | 2.22 | 1.87-2.43 | ||
| Baseline SMI level | <0.01 | <0.01 | |||||
| <43 (men), <41 (women) | 309 | 1.00 | 1.00 | ||||
| ≥43 (men), ≥41 (women) | 230 | 1.73 | 1.19-2.52 | 1.63 | 1.29-2.32 | ||