Table 1.
Differences of the characteristics according to the subcategorized groups of HT.
| All patients (n = 549) | Patients with HT (n = 279) | |||||
|---|---|---|---|---|---|---|
| No HT (n = 270) | HT (n = 279) | P-value | HI (n = 148) | PH (n = 131) | P-value | |
| Demographics | ||||||
| Age (y), mean ± SD | 69.1 ± 12.1 | 68.9 ± 12.6 | 0.815 | 69.3 ± 11.8 | 68.4 ± 13.4 | 0.548 |
| Male, n (%) | 181 (67.0) | 85 (30.5) | 0.530 | 103 (69.6) | 91 (69.5) | 0.981 |
| Risk factors, n (%) | ||||||
| Hypertension | 189 (70.0) | 177 (63.4) | 0.103 | 99 (66.9) | 78 (59.5) | 0.203 |
| Diabetes mellitus | 75 (27.8) | 69 (24.7) | 0.417 | 35 (23.6) | 34 (26.0) | 0.656 |
| Coronary heart disease | 14 (5.2) | 32 (11.5) | 0.008* | 18 (12.2) | 14 (10.7) | 0.700 |
| Atrial fibrillation | 26 (9.7) | 104 (37.3) | <0.001** | 43 (29.1) | 61 (46.6) | 0.003* |
| History of stroke | 31 (11.5) | 40 (14.3) | 0.319 | 25 (16.9) | 15 (11.5) | 0.196 |
| Cigarette smoking | 115 (42.6) | 122 (43.7) | 0.788 | 68 (45.9) | 54 (41.2) | 0.427 |
| SBP (mmHg), mean ± SD | 158 ± 23 | 149 ± 22 | <0.001** | 152 ± 22 | 146 ± 22 | 0.021* |
| DBP (mmHg), mean ± SD | 82 ± 14 | 83 ± 14 | 0.546 | 83 ± 14 | 82 ± 14 | 0.505 |
| Baseline NIHSS, median (IQR) | 3 (1–5) | 10 (5–13) | <0.001** | 7 (3–12) | 11 (7–14) | <0.001** |
| Stroke mechanisms, n (%) | <0.001** | 0.002* | ||||
| Large-artery atherosclerosis | 245 (90.7) | 157 (56.3) | 97 (65.5) | 60 (45.8) | ||
| Cardioembolism | 20 (7.4) | 118 (42.3) | 49 (33.1) | 69 (52.7) | ||
| Others | 5 (1.9) | 4 (1.4) | 2 (1.4) | 2 (1.5) | ||
| Infarct location, n (%) | ||||||
| Anterior circulation | 183 (67.8) | 257 (92.1) | <0.001** | 133 (89.9) | 124 (94.7) | 0.138 |
| Posterior circulation | 126 (46.7) | 117 (41.9) | 0.265 | 68 (45.9) | 49 (37.4) | 0.149 |
| Large infarct volume, n (%) | 5 (1.9) | 117 (41.9) | <0.001** | 51 (34.5) | 66 (50.4) | 0.007* |
| Treatment in hospital, n (%) | ||||||
| Thrombolysis | 5 (1.9) | 20 (7.2) | 0.003* | 7 (4.7) | 13 (9.9) | 0.093 |
| Anticoagulant | 26 (9.7) | 84 (30.1) | <0.001** | 38 (25.7) | 46 (35.1) | 0.086 |
| Antiplatelet | 248 (92.9) | 154 (55.2) | <0.001** | 86 (58.1) | 68 (51.9) | 0.299 |
| Neutrophil count, mean ± SD | 4.2 ± 1.4 | 6.3 ± 3.3 | <0.001** | 5.7 ± 3.0 | 7.0 ± 3.6 | 0.001 |
| Platelet count, mean ± SD | 207.0 ± 51.2 | 198.5 ± 67.3 | 0.096 | 203.5 ± 66.7 | 190.0 ± 63.4 | 0.085 |
| NPR, median (IQR) | 19.1 (14.8–24.8) | 30.1 (20.5–44.7) | <0.001** | 26.6 (17.9–38.3) | 36.8 (23.7–49.2) | <0.001** |
HT, hemorrhagic transformation; HI, hemorrhagic infarct; PH, parenchymal hematoma; SD, standard deviation; SBP, systolic blood pressure; DBP, diastolic blood pressure; IQR, interquartile range; NPR, neutrophil-to-platelet ratio;
*
P < 0.05;
**
P < 0.001.