Table 1.
Demographic data | Patients, no. | P value | ||
---|---|---|---|---|
Total patients (n = 122) | Combined echinocandins (n = 52) | Noncombined echinocandins (n = 70) | ||
Sex (M/F) | 112/10 | 45/7 | 67/3 | 0.096 |
Age (y) | 42.15 ± 13.90 | 41.43 ± 12.99 | 43.31 ± 15.29 | 0.462 |
Recent CD4 count (cells/μL) | 59.24 ± 66.86 | 64.64 ± 66.43 | 51.24 ± 67.35 | 0.275 |
Number of hospitalization days | 19.93 ± 9.73 | 19.36 ± 10.42 | 20.92 ± 8.45 | 0.409 |
Treatment | ||||
TMP-SMX (80 mg-400 mg, tid) | 122 | 52 | 70 | NA |
Clindamycin (800 mg, q8h) | 122 | 52 | 70 | NA |
Echinocandins (50 mg, qd) | 52 | 52 | 0 | NA |
Glucocorticoid (40 mg, bid) | 122 | 52 | 70 | NA |
Clinical outcome | ||||
PaO2/FiO2> 200 mmHg/PaO2/FiO2 ≤ 200 mmHg | 100/22 | 45/7 | 55/15 | 0.258 |
Survival/death | 103/19 | 47/5 | 56/14 | 0.118 |