Table 2.
Odds ratios of likelihood of lymph node metastasis stratified by seventh TNM staging using polytomous logistic regression.
| Variable | N1 metastasis (n = 30) | N2 metastasis (n = 70) | ||
|---|---|---|---|---|
| Odds ratio (95% CI) | p value# | Odds ratio (95% CI) | p value# | |
| Male gender | 2.366 (0.726-7.707) | 0.153 | 2.019 (0.868-4.697) | 0.103 |
| Chronic pulmonary disease | 1.827 (0.665-5.021) | 0.242 | 1.231 (0.489-3.102) | 0.659 |
| Smoking history | 0.479 (0.138-1.663) | 0.246 | 0.217 (0.080-0.590) | 0.003 |
| Respiratory- or cancer-related symptoms | 1.558 (0.692-3.508) | 0.284 | 0.741 (0.374-1.467) | 0.389 |
| Adenocarcinoma histology | 1.742 (0.619-4.901) | 0.293 | 0.849 (0.330-2.181) | 0.733 |
| Consolidation size (cm) | 5.449 (2.817-10.541) | <0.001 | 8.640 (5.002-14.923) | <0.001 |
| Central location | 1.069 (0.448-2.547) | 0.881 | 0.508 (0.255-1.014) | 0.055 |
| Clinical nodal stage on CT | ||||
| Enlarged LNs in N1 station | 11.424 (3.316-39.360) | <0.001 | 14.046 (4.226-46.682) | <0.001 |
| Enlarged LNs in N2 station | 1.615 (0.582-4.480) | 0.357 | 8.703 (4.326-17.509) | <0.001 |
| Levels of serum CEA (ng/ml) | 0.932 (0.806-1.077) | 0.340 | 1.063 (1.027-1.099) | 0.001 |
# p value represented the comparison with N0 patients.