Table 8.
Effects of LS, LSA, LSB, LSC, and LSD on TNF-α and IL-6 levels in urine and serum of rats within 24 hours after administration.
| Group | Urine | Serum | ||
|---|---|---|---|---|
| TNF-α | IL-6 | TNF-α | IL-6 | |
| Control | 145.23 ± 22.52 | 82.98 ± 13.99 | 143.26 ± 28.06 | 72.33 ± 14.42 |
| Furosemide | 143.63 ± 27.57 | 72.49 ± 13.88 | 157.04 ± 18.19 | 73.00 ± 13.80 |
| LS-H | 124.22 ± 13.81 | 74.28 ± 15.85 | 132.04 ± 29.98 | 65.00 ± 16.58 |
| LS-M | 133.71 ± 10.65 | 71.04 ± 15.41 | 139.90 ± 26.89 | 68.20 ± 13.81 |
| LS-L | 140.29 ± 12.81 | 78.68 ± 16.32 | 144.14 ± 14.82 | 69.83 ± 16.67 |
| LSA-H | 129.00 ± 16.04 | 72.29 ± 11.08 | 135.28 ± 30.58 | 74.12 ± 12.77 |
| LSA-L | 150.42 ± 21.77 | 66.29 ± 13.32 | 125.14 ± 12.81 | 70.25 ± 11.50 |
| LSB-H | 142.03 ± 15.04 | 78.49 ± 13.28 | 152.62 ± 28.04 | 69.88 ± 13.63 |
| LSB-L | 133.51 ± 10.80 | 69.42 ± 13.98 | 139.21 ± 31.27 | 71.76 ± 16.86 |
| LSC-H | 131.41 ± 21.70 | 69.89 ± 12.69 | 146.63 ± 24.64 | 62.38 ± 11.05 |
| LSC-L | 130.78 ± 19.43 | 61.23 ± 12.00 | 150.14 ± 14.18 | 73.59 ± 12.98 |
| LSD-H | 146.98 ± 23.31 | 71.45 ± 6.88 | 139.26 ± 21.28 | 73.82 ± 19.00 |
| LSD-L | 140.21 ± 19.62 | 81.43 ± 14.91 | 134.78 ± 32.01 | 75.81 ± 15.07 |
The values are reported as mean ± SD for 8 rats in each group.