Table 3.
Effect of Bixa orellana leaf hydroethanolic extract on intestinal transit in mice.
| Treatment | ITL (cm) | CCL (cm) | PI (%) | Inhibition (%) |
|---|---|---|---|---|
| NC | 51.80 ± 1.50 | 39.60 ± 3.00 | 76.45 ± 5.01 | — |
| AT0.3 | 48.20 ± 0.60 | 23.20 ± 1.10 | 48.13±1.71∗∗ | 37.04 |
| HEBo50 | 38.20 ± 0.60 | 21.10 ± 1.10 | 55.23±2.28∗∗ | 27.75 |
| HEBo100 | 49.40 ± 1.60 | 25.10 ± 3.00 | 50.81±0.89∗∗ | 33.54 |
| HEBo200 | 47.00 ± 1.30 | 22.30 ± 3.10 | 47.45±2.68∗∗ | 37.94 |
Values are expressed as mean ± S.E.M (n = 5). ITL: intestine total length; CCL: charcoal covered length; PI: peristaltic index; NC: normal control; AT0.3: atropine sulfate 0.3 mg/kg; HEBo25, HEBo50, HEBo100, and HEBo200: hydroethanolic extract of Bixa orellana leaves, respectively, at 25, 50, 100, and 200 mg/kg. Significant difference: ∗∗P < 0.01 compared with NC.