Table 4.

Effect of the hydroethanolic extract of Bixa orellana leaves on the mass of the small intestine and its contents in mice.

Treatment (mg/kg)	Mass of small intestine with content (g)	Mass of empty small intestine (g)	Mass of small intestinal content (g)
NC	1.13 ± 0.02	0.92 ± 0.09	0.21±0.01∗∗
DC	1.38 ± 0.19	1.01 ± 0.09	0.37 ± 0.13
LOP5	1.07 ± 0.03	0.81 ± 0.07	0.26±0.06∗∗
HEBo50	1.23 ± 0.08	0.90 ± 0.09	0.33 ± 0.04∗b
HEBo100	1.43 ± 0.11	1.15 ± 0.08	0.28±0.07∗∗b
HEBo200	1.38 ± 0.07	1.14 ± 0.09	0.24±0.09∗∗a

Values are expressed as mean ± S.E.M (n = 5). NC: normal control; DC: diarrheal control; Lop5: Loperamide 5 mg/kg; HEBo50, HEBo100, and HEBo200: hydroethanolic extract of Bixa orellana leaves, respectively, at 50, 100, and 200 mg/kg. Significant difference: ^∗P < 0.05 and ^∗∗P < 0.01 compared with DC; ^aP < 0.05 and ^bP < 0.01 compared with NC.