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Klotho attenuated H2O2-induced intracellular oxidative stress status. SOD activity, MDA formation, and ROS production were assessed. (a, b) The level of ROS in hPDLSCs was measured by DCFH-DA through a fluorescence microscope (a) and flow cytometry (b); (c) the MDA level and (d) SOD level in hPDLSCs. Scale bars: 50 μm. Magnification: 200x. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001 versus control group.
