Table 2.
Comparison between fragile X syndrome (FXS) with EEG abnormalities (IEDs) and without EEG anomalies (NIEDs) for polysomnographic macrostructural parameters. This table shows the differences between fragile X syndrome (FXS) children with interictal epileptiform discharges (IEDs) and without them (NIEDs) for polysomnographic macrostructural parameters: interquartile range (IQR); time in bed (TIB-min); sleep partial time (SPT-min); total sleep time (TST-min); sleep onset latency (SOL-min); first REM latency (FRL-min); stage shifting/h (SS-h); awakenings per hour (AWN-h); sleep efficiency percentage (SE%); wake after sleep onset percentage (WASO%); N1, N2, and N3 stage percentages; arousal indexes during the NREM and REM periods; apnea/hypopnea index (AHI); oxygen desaturation index (ODI); oxygen saturation (SpO2); nadir and desaturation percentage levels; and periodic limb movement index (PLMI).
| FXS IEDs (N = 13) | FXS NIEDs (N = 14) | |||||
|---|---|---|---|---|---|---|
| Median | IQR | Median | IQR | z value | p | |
| TIB-min | 499 | 459.2-539 | 493 | 444.3-535.2 | -0.728 | 0.46 |
| SPT-min | 518 | 505-529 | 474.75 | 405-500.5 | -3.252 | 0.001∗ |
| TST-min | 432.5 | 419.5-444 | 411.25 | 319.5-422 | -3.058 | 0.002∗ |
| SOL-min | -1 | -59-15.5 | 35.39 | 14-69.5 | 2.135 | 0.03 |
| FRL-min | 90.5 | 90.5-112 | 90.5 | 90.5-114 | 1.396 | 0.16 |
| SS-h | 6.2 | 5.3-7.9 | 9.45 | 6.2-10.8 | 1.774 | 0.07 |
| AWN-h | 6.8 | 5.2-8.3 | 7.6 | 5.8-10.5 | 1.166 | 0.24 |
| SE% | 83.70 | 80.45-94.36 | 77.57 | 71.93-84.15 | -1.941 | 0.05 |
| WASO% | 16.50 | 16.14-16.93 | 16.52 | 10.01-17.08 | -0.194 | 0.84 |
| N1% | 2.99 | 2.92-3.06 | 3.103 | 2.95-4.625 | 1.602 | 0.10 |
| N2% | 30.01 | 29.36-30.79 | 27.76 | 23.74-31.06 | -0.922 | 0.35 |
| N3% | 26.73 | 26.15-27.42 | 29.19 | 27.67-32.66 | 3.300 | 0.001∗ |
| REM% | 23.74 | 21.78-25.40 | 22.29 | 20.86-27.70 | -0.58 | 0.56 |
| NREM arousal index | 5.38 | 4.79-6.81 | 5.75 | 4.83-6.75 | 0.24 | 0.80 |
| REM arousal index | 9.63 | 9.01-10.13 | 9.34 | 8.38-9.84 | -1.165 | 0.24 |
| AHI | 10.23 | 9.64-10.61 | 9.76 | 9.04-10.04 | 0.922 | 0.35 |
| ODI | 4.32 | 4.08-4.82 | 4.05 | 3.48-4.92 | -1.21 | 0.22 |
| SpO2% | 94.22 | 93.53-94.56 | 92.58 | 91.87-94.03 | -2.23 | 0.02 |
| SpO2 nadir% | 90.50 | 89.65-91.17 | 89.91 | 89.13-90.90 | -0.776 | 0.43 |
| SpO2 desat% | 7.42 | 6.97-8.46 | 7.82 | 7.23-8.24 | 0.728 | 0.46 |
| PLMI | 5.83 | 5.06-6.81 | 6.76 | 6.01-7.96 | 1.213 | 0.22 |