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Effects of hollow 2D-BNNs on cellular and in vivo subcutaneously injected prostate cancer models. (A) BA or hollow 2D-BNNs with controlled B release resulting into different LDH release and caspase-3/7 activity in LNCaP prostate cancer, which is responsible for necrosis and apoptosis, respectively; (B) effects of saline, BA, and hollow BNNs-b spheres on mice pre-injected with LNCaP prostate cancer cells (Li et al., 2017).
