Figure 3.
Volcano plots of differentially expressed genes (DEGs) that were derived from microarray analysis of non-invasive NFPAs (A) and invasive NFPAs (B) compared to control tissues. The native log10 [false discovery rate (FDR) adjusted p-values] in the y-axis was plotted against the average log2(fold changes in expression) in the x axis. DEGs were determined using Limma followed by FDR correction. Horizontal dashed line indicated the threshold for significance (FDR adjusted p < 0.05) and vertical dashed line indicated the upregulated (right side) and downregulated (left side) probes.