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. 2019 Dec 5;2019:1785428. doi: 10.1155/2019/1785428

Table 3.

The available treatment modalities, the medications used, and the outcomes of treatment in some studies.

Study Available treatment modality Available hormonotherapy drugs Outcome
Diallo et al. [8] Surgical ADT (76.3%), medical ADT (22.4%) Cyproterone acetate 8% castrate resistant
Botcho et al. [9] Surgical ADT (38.6%), medical ADT, both (18.9%) Cyproterone acetate, flutamide, LHRH analogue, chemotherapy
Tengue et al. [12] Surgical ADT (34.5%), medical ADT (12.5%), both (46.1%) Cyproterone acetate, flutamide 15.1% mortality
Kirakoya et al. [10] Surgical ADT (24.3%), medical ADT (62.2%), both (13.4%) Cyproterone acetate, LHRH analogue 10.9% mortality
Kaboré et al. [14] Surgical ADT (43.3%), medical ADT (19%), both (9.5%) Cyproterone acetate, LHRH analogue
Wasike and Magoha [15] Mostly surgical ADT, few medical ADT Low-dose stilboestrol
Badmus et al. [19] Surgical ADT (71.9%), medical ADT (24.3%), both (22.2%) Stilboestrol, bicalutamide, goserelin, flutamide 5-year overall survival (7.4%)
Yeboah et al. [21] Neoadjuvant hormonotherapy ± medical ADT, EBRT, brachytherapy, TUIP, TURP Docetaxel, LHRH analogue, stilboestrol, bicalutamide /flutamide 11% hospital mortality
Ekwere and Egbe [13] Surgical ADT and medical ADT Stilboestrol 0% 5-year overall survival
Konan et al. [22] Surgical ADT (86.2%), medical ADT (13.7%) Cyproterone acetate, LHRH analogue 16.2% mortality
Sow et al. [23] Group 1: surgical ADT and medical ADT only
Group 2: cytoreductive therapy + castration
Group 1: 6-month median (OS)
Group 2: 8-month median (OS)

ADT: androgen deprivation therapy; EBRT: external beam radiation therapy; LHRH: luteinizing hormone-releasing hormone; OS: overall survival; TUIP: transurethral incision of the prostate; TURP: transurethral resection of the prostate. Cytoreductive therapy includes open prostatectomy or TURP.