Table 1.
Patient characteristics at baseline
| Gender (no. of patients, F/M) | 204/287 |
| Age (mean ± SD, years) | 63 ± 13 |
| Cardiac rhythm (no. of patients, %) | |
| Sinus | 397 (81) |
| Atrial fibrillation | 88 (18) |
| Atrial extrasystoles | 6 (1) |
| SAPSII (mean ± SD) | 63 ± 13 |
| Type of shock (no. of patients, %) | |
| Septic | 347 (71) |
| Hypovolemic | 100 (20) |
| Cardiogenic | 23 (5) |
| Vasoplegic (non-septic) | 21 (4) |
| Reasons for fluid administration (no of patients, %)a | |
| Hypotension | 101 (21) |
| Tachycardia | 201(41) |
| Oliguria | 220 (45) |
| Skin mottling | 54 (11) |
| Tissue hypoxia | 264 (54) |
| Mechanical ventilation (no. of patients, %) | 327 (67) |
| Tidal volume (mean ± SD, mL/kg of PBW) | 6.3 (0.8) |
| ARDS (no. of patients, %) | 295 (60) |
| Sedation (no. of patients, %) | 319 (65) |
| Lactate (mean ± SD, mmol/L) | 3.1 (1.2) |
| Patients receiving NE at baseline (no. of patients, %) | 346 (71) |
| NE dose at baseline (median [25–75% IQ] μg/kg/min | 0.7 [0.6–1.6] |
N = 491
ARDS acute respiratory distress syndrome, NE norepinephrine, SAPS II simplified acute physiology score, IQ interquartile
aSeveral reasons might have been present in a patient simultaneously