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. 2019 Aug 31;18(2):419–428. doi: 10.1007/s40200-019-00435-w

Table 3.

Correlation coefficients between biomarkers and parameters of cardiac autonomic function

Variable ∆ HR VR ∆DBP 30/15 ratio ∆SBP mean NN SDNN RMSSD pNN50 TP LF power HF power LF/HF ratio
IL-6 −.03 −.03 −.011 −.011 .11 −.16 −.20 −.10 −.002 −.34* −.36* −.17 .009
IL-18 −.18 −.16 −.17 −.04 .007 −.03 −.18 −.28 −.53** −.25 −.21 −.34* .21
hsCRP −.4** −.008 −.23 −.32* −.03 .03 −.24 −.40** −.36 −.35* −.31* −42** .22
NO .55** 0.05 .10 .46** .09 .05 .26 .65** .01 .30* .13 .32* −.25
eNOS .50** −.006 .10 .46** .14 −.14 −.06 .43** −.07 .07 −.002 .17 −.20
ET-1 .55** −.05 −.09 −.18 −.07 −.02 −.001 −.22* .03 −.03 −.02 −.18 .22

IL: interleukin; hsCRP: high-sensitivity C-reactive protein; NO: nitric oxide; eNOS: endothelial nitric oxide synthase; ET-1: endothelin-1; mean NN: average of N-N intervals; SDNN: standard deviation of N-N intervals; RMSSD: root mean square of successive differences between adjacent R-R intervals; pNN50: percentage of consecutive N-N intervals that differ by more than 50 ms; TP: total power; LF: low frequency; HF: high frequency; LF/HF ratio: ratio of low and high frequency power; ∆HR: change in heart rate during deep breathing test; VR: valsalva ratio; 30/15 ratio: ratio of R-R interval during 30th and 15th second of the head-up tilt test; ∆DBP: change in diastolic blood pressure during hand grip test; ∆SBP: change in systolic blood pressure during head-up tilt test; *p < .05; **p < .01