Table 1.
Baseline Clinical Characteristics
| N=225 | RAP ≤10 mm Hg (n=134) | RAP >10 mm Hg (n=94) | P Value | |
|---|---|---|---|---|
| Age at beginning of study, y | 34±16 | 33±12 | 35±13 | 0.136 |
| Male | 113 (50) | 63 (47) | 50 (53) | 0.105 |
| Age at TOF repair, y | 6 (3–14) | 5 (3–10) | 7 (4–17) | 0.092 |
| Prior palliative shunt | 141 (62) | 78 (58) | 63 (67) | 0.412 |
| TOF–pulmonary atresia | 87 (39) | 48 (36) | 39 (41) | 0.341 |
| Transannular patch repair | 122 (54) | 74 (55) | 48 (51) | 0.534 |
| Prior pulmonary valve replacement | 161 (72) | 92 (69) | 69 (73) | 0.348 |
| Prior heart failure hospitalization | 26 (12) | 8 (6) | 18 (19) | 0.003 |
| Loop diuretics | 47 (21) | 18 (13) | 29 (31) | 0.005 |
| RAAS antagonist | 56 (25) | 22 (16) | 34 (36) | <0.001 |
| β‐Blocker | 35 (16) | 12 (9) | 23 (24) | 0.004 |
| Comorbidities | ||||
| Atrial fibrillation | 63 (28) | 21 (16) | 42 (45) | <0.001 |
| Atrial flutter/tachycardia | 56 (25) | 26 (19) | 30 (32) | 0.026 |
| Chronic kidney disease | 17 (8) | 8 () | 9 (105) | 0.323 |
| Hypertension | 71 (32) | 37 (28) | 34 (36) | 0.481 |
| Hyperlipidemia | 95 (42) | 49 (37) | 46 (49) | 0.287 |
| Coronary artery disease | 25 (11) | 12 (9) | 13 (14) | 0.375 |
| Current or prior smoker | 45 (20) | 22 (16) | 23 (25) | 0.346 |
| Diabetes mellitus | 33 (15) | 8 (6) | 25 (27) | <0.001 |
| Obesity | 52 (23) | 28 (21) | 24 (26) | 0.219 |
Data are presented as mean±SD, median (interquartile range), or number (%). Chronic kidney disease is defined as stage ≥3 (creatinine clearance <60 mL/min). RAAS indicates renin–angiotensin–aldosterone system; RAP, right atrial pressure; TOF, tetralogy of Fallot.