Table I.
Summary of parameters in the 6 patients with metastatic pathological fracture of proximal femur.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | |
|---|---|---|---|---|---|---|
| Age (years old) | 56 | 73 | 64 | 56 | 59 | 63 |
| White cell count (X109/L) | 8.6 | 12.58 | 7.39 | 20.83 | 9.66 | 8.05 |
| Hematocrit (%) | 35.8 | 40.5 | 35.1 | 41.5 | 40.7 | 30 |
| Charlson Comorbidity Index score | 7 points | 10 points | 11 points | 7 points | 8 points | 8 points |
| Modified Bauer Score | 1 point | 0 point | 2 points | 0 point | 1 point | 0 point |
| Scandinavian Sarcoma Group (SSG) survival scoring | 1 point (Group B) | 0 point (Group C) | 1 point (Group B) | 0 point (Group C) | 1 point (Group B) | 1 point (Group B) |
| Metastatic sites from pre-operative staging | Lung, lymph nodes, adrenal & bone metastases | Lung, liver, adrenal and bone metastases | Lung, liver and bone metastases | Nodal, lung, adrenal and bone metastases. | Lungs and bone metastases | Lung, liver, adrenal, renal and bone metastases |
| Site of pathological fracture | Subtrochanteric | Neck of femur (and tibial lytic lesion) | Subtrochanteric | Neck of femur | Subtrochanteric | Subtrochanteric fracture and lesions involving whole femur |
| Operation time | 150 minutes | 265 minutes (2 procedures) | 152 minutes | 420 minutes | 220 minutes | 305 minutes (2 procedures) |
| Estimated blood loss | 1500mls | 400 mls | 400 mls | 800 mls | 1500 mls | 4000mls |
| Implant used to reconstruct the modified unipolar hemiarthroplasty (MUH) |
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| Post-operation hospital stay | 11 days | 16 days, transferred to nearby hospital | 5 days | Succumbed to disease at day 36 post-operation | 9 days | 9 days |
| Histopathological examination (HPE) results | Metastatic anaplastic carcinoma of the thyroid | Metastatic adenocarcinoma, most likely from lungs | Metastatic carcinoma, most probably from renal cell carcinoma | Metastatic adenocarcinoma, most likely from lungs | Metastatic adenocarcinoma from the rectum | Metastatic adenocarcinoma, most likely primary from the lung |
| Complications from surgery | None | Prolonged ICU admission for 15 days | Surgical site infection | None | None |
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| Survival duration post-operation | 2 months | 2 months | 3 months | 36 days | 11 months | 4 months |