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. 2019 Nov 18;10(11):789. doi: 10.3390/mi10110789

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Pharmacological modulation of neuronal responses through the collagen membrane. (a) Schematic view of the experiment. The implanted tube device was filled with ACSF (control) or gabazine dissolved in ACSF. (b) Forelimb-evoked neuronal activity before (upper panels) and after administering gabazine (lower panels). (c) Representative time course of optical signals collected from the same brain regions before and after gabazine was administered. Scale bar in (b), 1 mm. A, anterior; L, lateral.