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. 2019 Nov 18;55(11):747. doi: 10.3390/medicina55110747

Figure 4.

Figure 4

(a) Western blot analysis for cytoplasmic IkB alpha showed high levels of cytoplasmatic IkB alpha in the group pretreated with the CBG–CBD combination at 5 µM dose. (b) Western blot analysis for nuclear NF-kb p65 showed a significant NF-κB nuclear translocation in the groups pretreated with both CBG-CBD combinations. *** p < 0.001, **** p < 0.0001 vs. LPS; #### p < 0.0001 LPS + CBG 2.5 µM + CBD 2.5 µM vs. LPS + CBG 5 µM + CBD 5 µM. Blots are representative of three independent experiments. The densitometry analysis of bands representing means ± SEM of three independent experiments in which levels of each protein were normalized for GAPDH.