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. 2019 Nov 5;8(11):553. doi: 10.3390/foods8110553

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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MCT inhibits the production of pro-inflammatory cytokines while enhancing anti-inflammatory cytokine secretion. IL-6 (A) and TNF-α (B) production of RAW 264.7 macrophages treated with conventional oil samples under LPS-stimulated conditions (n = 3). Pro-inflammatory cytokine, IL-6 (C), and anti-inflammatory cytokine, IL-10 (D) secretion by mice BMDMs under non-polarized (M0), M1, and M2 polarized conditions (n = 7). The quantification of cytokines in culture supernatants was determined by ELISA. Data are indicated as mean ± SEM, and statistical significance is presented with different letters (p < 0.05, N.S. means no significant difference, N.D. means not detected) within each M0, M1, and M2 column (C,D).