Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 16;9:19161. doi: 10.1038/s41598-019-55605-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Investigation of C-PC effect on the cancer cells’ COX-2 expression in vitro and in vivo. (A) Flow cytometry analyses of COX-2 expression at the CT-26 cancer cells after incubation with different concentrations of C-PC (50, 100, and 200 µg/mL) and radiation therapy. The control cells were treated with PBS. The unstained cells were not incubated with anti-COX-2 antibody to identify the FL1-H+ and FL1-H- regions (FL1-H+: COX-2 positive region, FL1-H-: COX-2 negative region). Also, a group of wells was just irradiated (6 Gy) to identify the radiation therapy effect on COX-2 expression. (B) Western blot analysis of COX-2 expression in the tumors of C-PC treated (lane 3) tumor-bearing mice. Lane 2 exhibits the no-treated tumor-bearing mice’s tumors as positive control. The lanes 1 and 4 are presenting the ladder and the lysed MCF-7 cells as the negative control, respectively. The figure displays the full-length blots with no cropping.