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. 2019 Oct 15;27:104615. doi: 10.1016/j.dib.2019.104615

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© 2019 Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — The effects of As₂O₃ on spleen tissues. (A). As₂O₃ decreased the volume of the spleen. (B). The spleen index in the CIA control group increased significantly compared with the normal control group. However, the spleen index of groups under As₂O₃ (2.0 or 5.0 mg/kg/day) and MTX treatment decreased significantly compared with the CIA control group. Splenic corpuscle proliferation and splenic sinus congestion in the CIA group increased significantly compared with the normal control group. However, splenic corpuscle proliferation and splenic sinus congestion in the As₂O₃ and MTX treatment groups decreased significantly compared with the CIA control group.