Table 7.
The effects of As2O3 on spleen tissues. Percentage of Th1 and Th2 cells in spleen lymphocytes. Were detected by flow cytometry.
| Group (n = 5) As.Oj (mg kg day) |
Index of spleen | Spleen Histological score | Thl (%) | Th2 (%) |
|---|---|---|---|---|
| NC | 2.1 | 0.8 | 1.9 | 5.2 |
| NC | 2.2 | 1.1 | 1.5 | 6.0 |
| NC | 1.9 | 1.2 | 2.0 | 5.5 |
| NC | 1.8 | 1.0 | 1.8 | 4.5 |
| NC | 2.0 | 1.3 | 1.3 | 5.0 |
| CIA | 4.8 | 2.7 | 4.5 | 2.2 |
| CIA | 4.6 | 2.6 | 5.0 | 2.0 |
| CIA | 5.1 | 2.5 | 4.0 | 1.5 |
| CIA | 5.2 | 3.2 | 5.5 | 2.5 |
| CIA | 4.5 | 3.5 | 3.5 | 1.8 |
| 1.0 | 4.0 | 2.3 | 4.3 | 2.8 |
| 1.0 | 4.3 | 2.4 | 5.0 | 2.3 |
| 1.0 | 4.5 | 2.1 | 3.5 | 2.0 |
| 1.0 | 4 2 | 2.8 | 4.8 | 3.5 |
| 1.0 | 3.9 | 3.0 | 3.0 | 3.2 |
| 2.0 | 3.6 | 1.8 | 3.5 | 3.8 |
| 2.0 | 3.9 | 2.0 | 4.0 | 2.9 |
| 2.0 | 4.0 | 1.7 | 3.0 | 3.0 |
| 2.0 | 4.2 | 2.0 | 4.2 | 3.5 |
| 2.0 | 3.2 | 2.8 | 3.0 | 4.0 |
| 5.0 | 3.4 | 1.4 | 2.7 | 4 2 |
| 5.0 | 3.2 | 1.1 | 2.5 | 4.5 |
| 5.0 | 3.0 | 1.7 | 3.0 | 4.0 |
| 5.0 | 3.5 | 1.2 | 1.5 | 3.5 |
| 5.0 | 2.9 | 2.0 | 2.2 | 4.8 |
| MTX | 2.6 | 1.2 | 2.5 | 4.8 |
| MTX | 3.0 | 1.3 | 2.2 | 4.3 |
| MTX | 2.8 | 1.5 | 3.0 | 3.9 |
| MTX | 3.2 | 1.8 | 1.4 | 5.2 |
| MTX | 2.7 | 1.0 | 2.1 | 5.0 |