Specifications Table

Subject area	Immunology
More specific subject area	Arthritis and Rheumatology
Type of data	Image, graph, figures, histogram.
How data was acquired	Flow cytometry (FC 500, Moflo XDP, Beckman Coulter); Real-time polymerase chain reaction (PCR) (Applied Biochemistry PCR system); Hematoxylin and eosin; immunofluorescence
Data format	Raw and Analysis
Experimental factors	Peripheral blood mononuclear cells (PBMCs) from treatment-naïve rheumatoid arthritis (RA) patients and synovial fluid mononuclear cells (SFMCs) from RA patients were freshly isolated and cultured in standard conditions in the presence of arsenic trioxide (As2O3); PBMCs and SFMCs were stained with fluorescent antibodies; RNA was extracted from PBMCs; spleen tissues were isolated from DBA/1J mice
Experimental features	The percentage of Treg, Th17, Th1 and Th2 in CD4+T cells in the presence of As2O3 was detected by flow cytometry; Treg and Th17 cell-related transcription factors were detected by quantitative real-time PCR.
Data source location	Department of Rheumatology, The First Affiliated Hospital, Harbin Medical University, Harbin, China
Data accessibility	Data are provided with this article
Related research article	Li. C, Zhang. J, Wang. W, Wang. H, Zhang. Y, Zhang. Z, Arsenic trioxide improves Treg and Th17 balance by modulating STAT3 in treatment-naive rheumatoid arthritis patients, Int Immunopharmacol, 2019,73:539–551. DOI:https://doi.org/10.1016/j.intimp.2019.05.001