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Neutrophil Extracellular Trap Formation
Maximum intensity projections of hiPSC and primary blood (PB) neutrophils. Both show characteristic multi-lobed nuclei in blue and the azurophilic granule protein neutrophil elastase in green with control treatment. On treatment with 100 nM PMA both hiPSC and primary blood neutrophils form an extracellular fibril matrix composed of granule protein and chromatin, characteristic of neutrophil extracellular traps. Scale bars, 10 μm.
