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Compound Library Screening Using Mtb-Infected iMAC
(A) Schematic illustration of individual steps in the compound library screening using H37Rv-GFP Mtb-infected iMACs.
(B and C) Dose-response curve for INH (B) and RIF (C) in H37Rv-GFP-infected iMACs (n = 3).
(D) Primary screening results. Compounds (CPD) showing over 100% cell survival and 100% inhibition of infection are indicated as purple dots.
