Fig. 4.

Exploration of model coefficients in the elderly cerebellum. a Scatter plot of age coefficients against their influence score (coefficient from Horvath [8]/coefficient of variation in our data). The 10 most influential loci (largest scores by absolute value) are plotted in black, b 10 most influential loci, with the ages represented as a rug on the right-hand side of each strip chart. The Horvath coefficients are shown in the center, and their sign is also denoted by the direction of the triangles, upward facing for positive and downward facing for negative. c Scatter plot of Horvath [8] coefficients against their linear-model age coefficients in our data. The 10 most influential probes are shown in black