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. 2019 Dec 16;19:352. doi: 10.1186/s12877-019-1361-2

Table 3.

Twenty-four patients with hepatic aminotransferase elevation after statin treatment

No. Age Sex Statin Before treatment After treatment Elevation levels Liver enzyme elevation time Recovery time
ALT AST ALT AST
1 80 ≃ 85 M Simvastatin 18 20 69 39 Mild 2 weeks /
2 80 ≃ 85 M Fluvastatin 21 19 70 37 Mild 1 month /
3 80 ≃ 85 M Simvastatin 16 16 165 143 Moderate 1 month 3 months
4 80 ≃ 85 F Fluvastatin 14 18 49 51 Mild 1 month /
5 80 ≃ 85 M Atorvastatin 22 16 123 121 Moderate 3 months 1 month
6 80 ≃ 85 M Fluvastatin 13 17 98 83 Mild 2 weeks /
7 85 ≃ 90 M Rosuvastatin 18 19 87 40 Mild 2 weeks /
8 80 ≃ 85 M Simvastatin 12 15 182 244 Moderate 1 month 1 month
9 ≥90 M Simvastatin 13 18 34 42 Mild 2 weeks /
10 80 ≃ 85 M Atorvastatin 27 22 1017 511 Severe 3 months 1 month
11 80 ≃ 85 M Fluvastatin 10 11 66 71 Mild 2 weeks /
12 80 ≃ 85 M Simvastatin 15 16 261 301 Moderate 2 months 2 weeks
13 85 ≃ 90 F Fluvastatin 23 25 51 49 Mild 3 months /
14 80 ≃ 85 F Pravastatin 19 17 107 48 Mild 2 months /
15 80 ≃ 85 M Fluvastatin 21 14 125 133 Moderate 2 weeks 1 month
16 80 ≃ 85 F Simvastatin 34 24 979 696 Severe 6 months 1 month
17 ≥90 M Fluvastatin 15 20 47 54 Mild 1 month /
18 85 ≃ 90 M Pravastatin 16 13 70 43 Mild 1 month /
19 80 ≃ 85 M Pravastatin 13 14 57 51 Mild 1 month /
20 80 ≃ 85 M Atorvastatin 16 15 75 48 Mild 2 months /
21 80 ≃ 85 M Atorvastatin 10 13 44 53 Mild 2 weeks /
22 80 ≃ 85 M Atorvastatin 24 24 76 80 Mild 1 month /
23 80 ≃ 85 M Fluvastatin 26 25 267 222 Moderate 1 month 2 weeks
24 80 ≃ 85 M Pravastatin 31 23 300 260 Moderate 1 month 1 month

M male, F female, ALT alanine aminotransferase, AST aspartate aminotransferase