Figure 1. Time and dose of 17-β-estradiol (E2) that promoted edema and eosinophil migration to the uterus. A, The uterus of animals injected with E2 (100 μg/kg, sc) was collected and weighed (w) 6, 12, and 24 h after injection. The sesame oil group (SO, sc) was used as control. B, E2 doses of 0.1, 1, 10, and 100 µg/kg (n=10/group) were given and the uterus was collected and weighed 24 h later. C and D, The uteruses of the two experiments were used for the eosinophil peroxidase assay, reported as absorbance (A492). Data are reported as means±SE (3 independent experiments; n=5). *P<0.05 compared with SO group. #P<0.05 compared with E2 dose in 24 h (one-way ANOVA with Tukey post hoc correction).
