Table 1.
Characteristics of the top SNPs being selected as important features for the ADNI-Discovery Dataset
| SNP | Location | Function | Gene | Gene summary | WILCOX | FREQ |
|---|---|---|---|---|---|---|
| rs429358 | 19:44908684 | Missense Variant | APOE | APOE is a protein coding gene which generates alipoprotein E, a fat-binding protein crucial in many mechanisms of the body. This gene is related to Alzheimer’s Disease and Lipopoprotein Glomerulopathy among others. | 0 | 1.000 |
| rs67836621 | 19:51186703 | Noncoding (Intergenic) | Adjacent: SIGLEC20P, LOC100133225 (Pseudogene) | Unknown | 8e-04 | 0.298 |
| rs9928727 | 16:9018042 | Noncoding (Intergenic) | Adjacent: LOC105371074 (Uncharacterized), C16orf72 | Unknown | 9e-04 | 0.269 |
| rs11602604 | 11:62231065 | Noncoding (Intergenic) | Adjacent: SCGB2A1, SCGB1D2 | Unknown | 3e-04 | 0.321 |
| rs6448799 | 4:11628425 | Intron Variant | HS3ST1 (LOC107986178) | HS3ST1 is a protein coding gene which is crucial to create heparan sulfate structures that participate in sulfotransferase activity. This gene is related to Arteriosclerosis and Coronary Heart Disease. | 6e-04 | 0.288 |
| rs16905109 | 8:134194872 | Noncoding (Intergenic) | Adjacent: LOC100419617 (Pseudogene), ZFAT | Unknown | 0.0011 | 0.383 |
| rs76566842 | 9:28296478 | Intron Variant | LINGO2 | LINGO2 is a protein coding gene for the Leicine-rich Repeat Neuronal Protein. This gene is related to the Essential Tremor disease. | 0.1619 | 0.327 |
| rs9863257 | 3:27586911 | Noncoding (Intergenic) | Adjacent: RNU1-96P, RPS27P11 | Unknown | 0.1955 | 0.323 |