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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Drug Alcohol Depend. 2019 Jan 4;195:140–147. doi: 10.1016/j.drugalcdep.2018.12.006

Fig. 2:

Fig. 2:

Duration of MDPV-induced elevations in HR (A) and BP (C) in male and female SD rats (mean + SD, n=7/sex). Filled symbols indicate significant difference between sexes at corresponding doses determined by two-way ANOVA with Holm-Sidak’s multiple comparison test. The area under the MDPV-induced HR (B) and BP (D) versus MDPV dose curves (AUC) showed females had significantly lower (*p<0.05 Welch’s t-test) duration of MDPV-induced CV effects than males.