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. 2019 Dec 16;15:452. doi: 10.1186/s12917-019-2164-6

Table 1.

Results of PPR experimental infection on goats according five severity criteria

Group Animal Mortality score Clinical score Tissue virus load score Hyperthermia duration (days) Swabs virus load score Severity score
I 1 2 13 2.2 6 1.6 82.2
2 1 15 2.8 8 2 91.4
II 3 2 14 2.7 9 1.9 94
4 3 17 3.7 7 2.3 110.4

Group I was infected by cell virus suspension with a titer of 6.2 logTCID50/ml. Group II was infected by infectious mashed tissue (lung and mesenteric node). both from the same isolate. For each individual goat. a severity score was calculated. We evaluated five criteria by significance: 1) Mortality. 2); Clinical scoring; 3) Viral load in post mortem tissue; 4) Hyperthermia duration; 5) Viral load in swabs (number of positive and cycle threshold (Ct) values). Each criteria has a coefficient of significance (5 point for criteria 1 to 1 point for criteria 5). The severity score is a cumulative value of each criteria score. Previously multiplied by the coefficient of significance