Table 1.
Group | Animal | Mortality score | Clinical score | Tissue virus load score | Hyperthermia duration (days) | Swabs virus load score | Severity score |
---|---|---|---|---|---|---|---|
I | 1 | 2 | 13 | 2.2 | 6 | 1.6 | 82.2 |
2 | 1 | 15 | 2.8 | 8 | 2 | 91.4 | |
II | 3 | 2 | 14 | 2.7 | 9 | 1.9 | 94 |
4 | 3 | 17 | 3.7 | 7 | 2.3 | 110.4 |
Group I was infected by cell virus suspension with a titer of 6.2 logTCID50/ml. Group II was infected by infectious mashed tissue (lung and mesenteric node). both from the same isolate. For each individual goat. a severity score was calculated. We evaluated five criteria by significance: 1) Mortality. 2); Clinical scoring; 3) Viral load in post mortem tissue; 4) Hyperthermia duration; 5) Viral load in swabs (number of positive and cycle threshold (Ct) values). Each criteria has a coefficient of significance (5 point for criteria 1 to 1 point for criteria 5). The severity score is a cumulative value of each criteria score. Previously multiplied by the coefficient of significance