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. 2019 Dec 16;17:221. doi: 10.1186/s12957-019-1755-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — miRNA-gene regulatory network. a A global view of the network. The network was constructed from common DEGs and deregulated miRNAs. The network contained 11 common deregulated miRNAs, 20 common DEGs, and 35 miRNA-gene pairs. The orange triangle represents miRNA, while the blue square represents DEG. b A subnetwork with hsa-miR-181a-5p as the central node. c A subnetwork with BCL2 as the central node. DEGs, differentially expressed genes