Table 3.
LncRNA expressions in CF parenchyma tissues
|
Up-Regulated LncRNAs |
Fold Change↑ | P-value | Type |
RNA length |
| MIR3615 | 13.9421449 | 0.028800825 | natural antisense | 565 |
| XLOC_009603 | 12.7909929 | 0.025368402 | intergenic | 873 |
| G083378 | 11.2370894 | 0.002389514 | intergenic | 763 |
| RP11-466A19.8 | 10.8534252 | 0.03983941 | intron sense-overlapping | 927 |
| LINC00176 | 10.6662478 | 0.012646718 | intronic antisense | 5264 |
| G012592 | 10.3110888 | 0.000140675 | intergenic | 1050 |
| G018678 | 9.6891061 | 0.036809781 | intergenic | 1310 |
| G044675 | 9.1156866 | 0.045874645 | intergenic | 1071 |
| POT1-AS1 | 8.7808728 | 0.027374905 | natural antisense | 3983 |
| XLOC_006737 | 8.2777265 | 0.012895875 | intergenic | 983 |
|
Down-regulated LncRNAs |
Fold Change↓ | P-value | Type |
RNA length |
| G065252 | 14.331561 | 0.028187016 | intergenic | 1056 |
| GSE61474_XLOC_034508 | 13.3814695 | 0.003626576 | intergenic | 1565 |
| LOC101928697 | 12.5462712 | 0.012533081 | bidirectional | 574 |
| G041222 | 12.3614159 | 0.018597696 | intergenic | 618 |
| AC099850.1 | 9.7851638 | 0.000389157 | intronic antisense | 1338 |
| LINC01023a | 8.861641 | 0.002639581 | intergenic | 457 |
| G027019 | 8.6429315 | 0.009020488 | intergenic | 777 |
| G035586 | 8.3415865 | 0.004331082 | intergenic | 3265 |
| RP11-667 M19.2 | 7.7994756 | 8.64985E-05 | intron sense-overlapping | 586 |
| G087905 | 7.5150766 | 0.042188797 | intergenic | 1443 |
The LncRNAs that are significantly up-regulated and down-regulated in CF parenchyma tissues compared to non-CF controls are listed. (aValidated by qPCR)