microCT assessments of BVF and TMD and histomorphometry measurements of BVF and BIC. (A) At day 14, the Scl-Ab group had more BVF than the vehicle group by t-test analysis (p < 0.05). Furthermore, the Scl-Ab group at day 28 presented the largest BVF through one-way ANOVA. (B) Assessment of TMD indicated no difference between Scl-Ab and vehicle groups. (C, D) The Scl-Ab group had the statistically greatest BIC and bone fill percentage at day 28 compared with the vehicle group, as analyzed by one-way ANOVA. ANOVA, analysis of variance; BVF, bone volume fraction; BIC, bone-implant contact; TMD, tissue mineral density.