FIG. 6.

Alignment of samples along the developmental time and identification of dynamically discordant transcripts. (A) Mouse embryo development and human in vitro differentiation samples aligned along DT. The PC2 values for mouse and human samples are plotted against DT. The DT can be represented as a common measure of maturity for in vitro differentiation and in vivo development. (B) Cross-species/cross-in vitro-in vivo comparison of transcript dynamics based on DT as a common time scale. Notable transcription factors are plotted along the developmental time. Other discordant transcripts are shown in Supplementary Figure S6. DT, unified developmental time. Color images available online at www.liebertpub.com/scd