Table 2.
Summary of In Vivo Functional Data of Tibialis Anterior Muscle at 8 Weeks Postinjury
| NR | BAM | KN | KN + I | KN + b | KN+I+b | KN + M | KN+M+I | KN+M+b | KN+M+I+b | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sample size (n) | 7 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 |
| Body wt (g) | 216 ± 0.9 | 206.6 ± 1.8 | 214.0 ± 4.3 | 206.1 ± 3.9 | 205.4 ± 2.6 | 194.8 ± 3.5 | 198.8 ± 2.3 | 202.9 ± 1.9 | 197.0 ± 5.3 | 199.8 ± 1.2 |
| TA muscle wet wt (mg) | 352.3 ± 16.6a | 385.0 ± 9.0b,c | 387.6 ± 16.8b,c | 370.3 ± 16.7a–d | 424.5 ± 14.4e | 364.8 ± 18.9a,c,d | 373.5 ± 13.9a–d,f | 355.7 ± 7.61a,b,d,f | 400.4 ± 13.2b,c,e | 392.5 ± 16.2b–e |
| Peak tetanic isometric torque | ||||||||||
| Nmm/kg body wt | 57.5 ± 3.8a | 50.0 ± 3.3a,b | 61.9 ± 5.8a,b | 66.5 ± 4.0c | 62.9 ± 5.0a,c,d | 56.1 ± 5.0a,b,d,e | 60.4 ± 5.3a–e | 51.1 ± 3.0a,b,e | 61.1 ± 3.1a,b,d,e | 66.6 ± 5.1a,c,d |
| Deficit (%)* | 28.0 ± 4.1a | 37.1 ± 4.1a,b | 23.3 ± 7.1a,b | 10.5 ± 5.3c | 18.6 ± 6.4a,c,d | 27.7 ± 6.4a,b,d,e | 22.9 ± 6.6a–e | 36.5 ± 3.6a,b,e | 27.3 ± 3.6a,b,d,e | 20.1 ± 6.0a,c,d |
| Nmm/g TA wet wt | 40.76 ± 1.5a | 33.4 ± 1.7a | 40.9 ± 3.6a | 44.1 ± 1.5a | 36.8 ± 3.4a | 37.6 ± 2.9a | 39.8 ± 2.8a | 36.1 ± 1.6a | 38.7 ± 2.6a | 41.0 ± 1.8a |
Values are mean ± SEM. Values denoted with the same letter are not significantly different (p > 0.05), whereas values without a similar letter denotation are significantly different (p < 0.05).
*
Deficit calculated from un-operated animals.
NR, no repair; SEM, standard error of the mean; TA, tibialis anterior; wt, weight.