Fig. 1.

Study selection process for the systematic literature review and meta-analysis of breast cancer (BC). *Exclusions include not phase II, not phase III or phase II with triple-negative breast cancer (TNBC) focus, phase II not TNBC focus, not phase II or phase III, and not TNBC focus phase II/I. ^†Exclusions include review articles, other study types, not recurrent/metastatic (R/M) of phase III/II data, and not TNBC-specific R/M. ^‡Exclusions include non-cancer outcomes focus, only quality-of-life data, study protocol, surgical intervention, model development, and only AE data. ^§Exclusions include other language, older report of the same study, and reference unavailable. ^‖Results from one study (phase III trial, study 301) based on internal communication with sponsor (Eisai); not published results. ^¶Results from Twelves et al.’s [9] and Pivot et al.’s [13] studies are both included based on the reported different treatment line outcomes