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. 2018 Aug 1;28(8):1004–1012. doi: 10.1089/thy.2018.0085

FIG. 2.

FIG. 2.

Distribution of histological diagnoses by sonographic pattern. (A) Distribution of histological diagnosis by Bethesda category and sonographic pattern. (B) Distribution of sonographic patterns by histological diagnosis. (C) Proportion of malignancies classified as low risk, intermediate risk, or high risk by sonographic pattern (excluded two intrathyroidal parathyroid carcinomas; see Methods section for definition of groups). FTC/HCC, follicular thyroid carcinoma/Hürthle cell carcinoma; FVPTC, follicular variant of papillary thyroid carcinoma; HP/AN/CLT, hyperplastic/adenomatous nodule or chronic lymphocytic thyroiditis; NIFTP, noninvasive follicular thyroid neoplasm with papillary-like nuclear features; Other PTC, other variants of papillary thyroid carcinoma different from FVPTC. aIncludes one intrathyroidal parathyroid adenoma. bIncludes two intrathyroidal parathyroid carcinomas, three medullary thyroid carcinomas, and one poorly differentiated thyroid carcinoma. Due to small cell counts, to compare the distribution of the histological diagnoses, NIFTPs and FVPTCs were collapsed into one group, and all other invasive cancers were collapsed into another group. Differences between AUS/FLUS and FN/HCN were statistically significant (p < 0.001). The distribution of histological diagnoses between sonographic patterns was also significantly different (p < 0.001 with Fisher's exact test for count data with a simulated p-value based on 2000 replicates). The low and intermediate suspicion patterns were collapsed into a single group for this analysis.