Table 2.

Associations Between UIC groups and All-Cause, Cardiovascular, and Cancer Mortality in NHANES III^a

			Adjusted
	Event N/total N	Unadjusted HR [CI]	Model 1bHR [CI]	Model 2cHR [CI]
All-cause mortality
Very low UIC	327/1398	0.91 [0.75–1.12]	0.88 [0.73–1.06]	0.93 [0.77–1.14]
Low UIC	679/2597	1.00 [0.87–1.16]	0.91 [0.80–1.0])	0.96 [0.84–1.09]
Normal UIC (reference)	1664/6500	1	1	1
High UIC	206/804	1.09 [0.83–1.44]	0.91 [0.70–1.18]	0.88 [0.66–1.17]
Very high UIC	283/965	1.32 [1.12–1.58]	1.20 [1.04–1.39]	1.19 [1.04–1.37]
Cardiovascular mortality
Very low UIC	71/1398	0.77 [0.58–1.03]	0.79 [0.60–1.06]	0.87 [0.66–1.15]
Low UIC	146/2597	0.87 [0.70–1.08]	0.79 [0.64–0.98]	0.87 [0.70–1.08]
Normal UIC (reference)	390/6500	1	1	1
High UIC	46/804	0.92 [0.55–1.52]	0.72 [0.42–1.23]	0.68 [0.38–1.22]
Very high UIC	64/965	1.34 [1.01–1.76]	1.18 [0.94–1.48]	1.16 [0.90–1.34]
Cancer mortality
Very low UIC	99/1398	1.45 [1.01–2.08]	1.26 [0.89–1.76]	1.34 [0.95–1.90]
Low UIC	177/2597	1.24 [0.92–1.65]	1.09 [0.82–1.44]	1.14 [0.87–1.49]
Normal UIC (reference)	395/6500	1	1	1
High UIC	51/804	1.26 [0.76–2.09]	1.09 [0.69–1.71]	1.09 [0.69–1.74]
Very high UIC	77/965	1.53 [1.03–2.28]	1.39 [0.92–2.10]	1.39 [0.93–2.07]

^aThe reference is normal UIC.

^bHR adjusted for age, sex, race/ethnicity, education status. and active smoking.

^cHR adjusted for diabetes, hypertension, hypercholesterolemia, previous cardiovascular disease, previous cancer, BMI, and eGFR in addition to covariates in Model 1.