Table 1.

miR-133a-3p Expression in Cells and Extracellular Vesicles after mir-133a Overexpression

	HEK293-mir-133a (CMV, unmodified)	HEK293-mir-133a-EXO (H1, modified)
Cellular miR-133a-3p	89,987 ± 15,179 (n = 7)	1695 ± 336 (n = 7)
EV miR-133a-3p	70,591 (n = 2)	1645.958 (n = 2)
EV/cellular	0.78	0.97
EV miR-202-5p	5 (n = 1)	0.3 (n = 1)

“n” indicates number of experiments. All expression levels are expressed as fold of cells expressing nontargeting controls. For cellular expression, mean ± SEM is listed. For EV expression, only the mean is listed because of the low replicate numbers.

CMV, cytomegalovirus; EV, extracellular vesicle; EXO, exosome; SEM, standard error of the mean.