2. Characteristics of interventions and comparators.
| Study | Type of toric IOL | Type of non‐toric IOL | Details of LRI | Nomogram |
| Dong 2015 | Tecnis Toric (Abbott Medical Optics) | Spherical IOL, unspecified | Conventional temporal clarity cornea incision phacoemulsification and spherical IOL implantation combined with LRIs on steep axial position. | Not specified |
| Freitas 2014 | AcrySof Toric (Alcon) | AcrySof Natural (Alcon) | LRIs were placed inside the limbus using a calibrated diamond knife with a preset blade depth of 600 μm. | Donnenfeld |
| Gangwani 2014 | M‐Flex multifocal toric (Rayner Intraocular Lenses) | M‐Flex multifocal non‐toric (Rayner Intraocular Lenses) | Both surgeons used an identical 600 μm guided steel blade (Micro Feather ophthalmic scalpel with aluminium handle, No: 7360G, Feather Safety Razor Co., Ltd.). The depth of the PCRIs was 600 μm. | Donnenfeld |
| Hirnschall 2014 | T‐Flex toric (Rayner Intraocular Lenses) | C‐Flex or Superflex non‐toric (Rayner Intraocular Lenses) | A CCI on the steep meridian was preferred and combined with a single opposite PCRI. In cases in which a CCI on the steep meridian was awkward, such as in cases of superonasal incisions in deep‐set eyes, a temporal incision combined with 2 PCRIs was created. In all cases, PCRIs were made at the end of surgery using a 600 μm guided steel blade (Micro Feather ophthalmic scalpel with aluminium handle No: 7360G, Feather Safety Razor Co., Ltd.) | Donnenfeld |
| Lam 2016 | Tecnis toric ZCT150, ZCT225 and ZCT300 (Abbott Medical Optics) | Tecnis monofocal ZCB00 (Abbott Medical Optics) | The LRI incision was made before the commencement of phacoemulsification using a 600 μm Accutome guarded diamond knife. | Nichamin Age and Pachymetry Adjusted nomogram |
| Leon 2015 | AcrySof IQ toric (Alcon) | AcrySof IQ Aspheric monofocal (Alcon) | Based on the procedure described by Langerman, a vertical limbal relaxing wound was created with a guarded micrometer diamond blade by making a groove concentric to the limbus. The incision depth was set at 600 μm equal to approximately 85% of the peripheral corneal thickness at the axis to be cut and the incisions were approximately a length of 3 mm. After the paired incision was made, the penetrating CCI was made along the steepest axis in the upper area for the cataract surgery, along the same axis as the LRI. | Nichamin Age and Pachymetry Adjusted nomogram |
| Liu 2014 | AcrySof toric (Alcon) | AcrySof (Alcon) | The incisions were as deep as 80–90% of the corneal thickness and were located in the peripheral cornea of the steep axis. | Gills and Gayon's |
| Mingo‐Botin 2010 | AcrySof Toric (Alcon) | AcrySof Natural (Alcon) | PCRIs were created inside the limbus using a calibrated diamond knife with the blade depth set at 600 μm. In eyes with against‐the‐rule astigmatism, the main incision for phacoemulsification was created to match the location of the LRI. At the end of surgery, the PCRIs were performed including the previous incision, and a paired incision was made on the opposite side. In eyes with with‐the‐rule astigmatism, both PCRIs were created on the steep axis before the globe was entered at the beginning of the procedure. | Nichamin Age and Pachymetry Adjusted nomogram |
| Nanavaty 2017 | T‐Flex (Rayner Intraocular Lenses) | Rayner C‐flex (Rayner Intraocular Lenses) | A single or double PCRI was placed on the limbus after draping and before starting cataract surgery using the recommendation from www.LRIcalculator.com and using 0‐ and 180‐degree ink marks as a reference and using the surgically induced astigmatism of 0.5 D at 120 degrees. After the participant had been draped, a standard 600 μm disposable PCRI blade (Feather, Osaka, Japan) was used to perform the PCRIs in all cases before any incisions for cataract surgery. | Donnenfeld |
| Titiyal 2014 | AcrySof IQ Toric IOL (Alcon) | AcrySof IQ Aspheric IOL (Alcon) | A 12‐blade radial keratotomy marker was placed on the 7.0 mm optical zone mark. Paired arcuate keratotomy incisions were made in the 7.0 mm optical zone. The 30‐degree paired arcuate keratotomy cuts were made on the steeper meridian using a micrometer‐guided diamond knife (Meyco) that was set at 100% of the thinnest paracentral pachymetry. | Nomogram not specified. |
CCI: clear corneal incision; IOL: intraocular lens; LRI: limbal relaxing incision; PCRI: peripheral corneal relaxing incision.