Figure 2.

One‐step synthesis of bioactive caged compounds. (A) Overview of generated photo‐caged compounds. Unprotected parent compounds were typically reacted with in situ generated 1 in the presence of DIEA in chloroform at 0 °C. In the case of N‐acetyl‐neuraminic acid, DMF was used to enhance solubility. Yields are given below each structure. (B) Cellular localization of photo‐caged compounds 6, 8, 9, 10, 11, 12, 13, 14. Image acquisition settings were optimized for each compound, larger fields of view and images acquired using identical settings for all compounds are displayed in Supplementary Figure S4 and S5 for comparison. Scale bars indicate 10 μm.