Table 1.

Standardized regression coefficients for the univariate linear regression analyses with childhood problem behavior predicted by the PRS for schizophrenia, depression, neuroticism, and wellbeing

			PRS schizophrenia				PRS depression				PRS neuroticism				PRS wellbeing
			β	SE	p‐Value	R 2	β	SE	p‐Value	R 2	β	SE	p‐Value	R 2	β	SE	p‐Value	R 2
Problem behavior age 5–6	Mother	Int	0.066	0.015	.026	.004	0.077	0.014	.009	.006	0.049	0.015	.098	.003	−0.037	0.015	.205	.002
		Ext	0.097	0.020	.001*	.011	0.049	0.020	.093	.004	0.018	0.020	.542	.002	−0.043	0.020	.149	.003
	Teacher	Int	0.009	0.020	.787	.001	−0.026	0.019	.409	.001	0.013	0.019	.671	.001	−0.013	0.019	.693	.001
		Ext	0.048	0.015	.133	.002	0.033	0.025	.300	.001	0.040	0.025	.210	.002	−0.046	0.025	.147	.002
Problem behavior age 11–12	Mother	Int	−0.031	0.026	.382	.001	0.063	0.023	.073	.004	0.046	0.024	.189	.002	0.000	0.024	1.00	–
		Ext	0.012	0.028	.739	–	0.045	0.026	.201	.002	0.071	0.026	.044	.005	−0.032	0.026	.367	.001
	Teacher	Int	−0.043	0.010	.286	.002	0.035	0.009	.385	.002	0.011	0.010	.265	–	−0.017	0.009	.678	.001
		Ext	0.069	0.013	.086	.005	0.061	0.012	.127	.004	0.075	0.013	.060	.006	−0.067	0.012	.096	.005
	Child	Int	0.040	0.022	.235	.003	0.072	0.021	.033	.006	0.092	0.021	.007	.009	−0.074	0.021	.028	.006
		Ext	0.024	0.037	.983	–	0.034	0.023	.315	.001	0.027	0.013	.426	.001	−0.046	0.023	.168	.002

Note: Polygenetic risk scores that are reported here were calculated based on a Gaussian Prior of 1. Gender was included as a covariate. Bold values indicate all significant findings.

Abbreviations: Ext, SDQ score for externalizing problem behavior; Int, SDQ score for internalizing problem behavior; PRS, polygenetic risk score; SDQ, strengths and difficulties questionnaire.

*Significant after multiple correction (based on p < .005).