Figure 1.

CytoMatrix: a support to entrap limited amounts of cytological material from MPEs. (a) Representative pictures of the plastic bio‐cassette containing CytoMatrix in the closed (left photo) and open (right photo) conformations. (b) The synthetic matrix restraining the biological material either derived from primary cancer cells directly isolated from MPEs and from established primary cell cultures grown in 2D or 3D conditions may be subjected to classical ICC steps: formalin fixation, paraffin inclusion, and microtome cut. 2D, two‐dimensional; MPE, malignant pleural effusions [Color figure can be viewed at wileyonlinelibrary.com]