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. 2019 Oct 8;112(6):1674–1683. doi: 10.1111/mmi.14397

Figure 2.

Figure 2

Genes involved in Tfp biogenesis in monoderms. All the genes are drawn to scale, with the scale bar representing 1 kb. Genes shaded in the same colour are likely to encode orthologous proteins based on sequence similarity, functional domain conservation and/or conserved synteny. Names of genes often mentioned in this review are listed at the bottom. No colour coding indicates genes with no clear homologs in other species. Genes with no name are identified by their ORF number in the corresponding genome, genes highlighted with an * have been shown to encode proteins dispensable for Tfp biogenesis but playing key roles in Tfp biology. The former nomenclature for the pilO gene in S. sanguinis is indicated within parentheses. The major pilin in C. perfringens has not been experimentally determined and has been attributed to pilA1 based on findings in C. difficile. The NCBI entries that were used to generate this figure are: PRJEA34687 (N. meningitidis), PRJNA331 (P. aeruginosa), PRJEB7884 (S. sanguinis), PRJNA79 (C. perfringens), PRJNA78 (C. difficile), PRJNA15630 (E. coli), PRJNA36 (V. cholerae), PRJNA32027 (C. crescentus), PRJNA40107 (A. actinomycetemcomitans), PRJNA13487 (B. breve) and PRJNA238160 (M. luteus).