K (number of studies) |
5, 10, 30 |
5, 10, 30 |
|
n or
(average (individual) study size—total of the two arms) |
20, 40, 100, 250 |
30 (12, 16, 18, 20, 84), |
|
For K=10 and K=30, the same set of unequal study sizes |
|
60 (24, 32, 36, 40, 168), |
|
is used twice or six times, respectively |
|
100 (64, 72, 76, 80, 208), |
|
|
|
160 (124, 132, 136, 140, 268) |
|
q (proportion of each study in the control arm) |
1/2, 3/4 |
1/2, 3/4 |
|
First series of within‐study variances: |
|
|
|
μ
|
0 |
0 |
B1, B2; B3, B4 |
(within‐study variances) |
(1,1), (1,2) |
(1,1), (1,2) |
|
τ
2 (variance of random effect) |
0(0.01)0.1(0.1)1 |
0(0.01)0.1(0.1)1 |
A1, A2; A3, A4 |
Second series of within‐study variances: |
|
|
|
μ
|
0 |
0 |
B5, B6 |
(within‐study variances) |
(10,10), (10,20) |
(10,10), (10,20) |
|
τ
2 (variance of random effect) |
0(0.1)1 |
0(0.1)1 |
A5, A6 |