Table 2.

The associations (odds ratios and 95% confidence intervals) of the covariates and trial status from univariable and multivariable logistic regression models

	Univariable (before multiple imputation)	Multivariable (after multiple imputation)
Age (years)
< 20	0.71 (0.41–1.24)	0.63 (0.34–1.16)
20–24	0.99 (0.75–1.32)	0.83 (0.60–1.14)
25–29	0.89 (0.70–1.14)	0.76 (0.58–1.00)
30–34	0.79 (0.63–0.98)	0.67 (0.52–0.87)
35–39	1.12 (0.93–1.36)	1.04 (0.83–1.30)
40–44	1.04 (0.87–1.26)	0.96 (0.78–1.19)
45–49	Reference	Reference
50–54	1.16 (0.96–1.40)	1.12 (0.90–1.38)
55–59	1.21 (0.99–1.47)	1.29 (1.02–1.62)
60–64	1.34 (1.07–1.68)	1.41 (1.09–1.84)
65–69	0.89 (0.67–1.18)	0.92 (0.66–1.29)
70–74	0.64 (0.40–1.01)	0.58 (0.34–1.00)
75–79	0.38 (0.17–0.83)	0.46 (0.20–1.09)
80–85	0.34 (0.08–1.46)	0.40 (0.09–1.80)
> 85	0.71 (0.08–6.12)	0.78 (0.06–9.85)
Body mass index	1.00 (1.00–1.01)	1.00 (0.99–1.00)
Female sex	0.66 (0.59–0.73)	0.53 (0.47–0.60)
Depression	0.60 (0.52–0.68)	0.59 (0.51–0.69)
Diabetes	1.14 (0.97–1.34)	0.97 (0.79–1.19)
Stroke	0.46 (0.24–0.87)	0.45 (0.22–0.93)
Myocardial infarction	0.71 (0.49–1.02)	0.78 (0.50–1.22)
Angina	0.23 (0.13–0.41)	0.19 (0.10–0.36)
Hypertension	1.01 (0.90–1.13)	0.95 (0.82–1.10)
Asthma	0.74 (0.62–0.88)	0.71 (0.58–0.88)
Number of previous systemics	0.49 (0.46–0.51)	0.42 (0.40–0.45)
Number of previous biologics	1.83 (1.71–1.96)	2.31 (2.13–2.50)
Psoriatic arthritis	1.27 (1.14–1.42)	1.03 (0.90–1.17)
Previous skin cancer	0.79 (0.54–1.16)	0.97 (0.62–1.53)
Ethnicity
White	Reference	Reference
Black	2.88 (1.86–4.46)	2.11 (1.26–3.54)
Asian	0.79 (0.61–1.02)	0.53 (0.40–0.71)
Other	0.70 (0.49–0.99)	0.54 (0.37–0.79)
Alcohol	0.93 (0.92–0.94)	0.92 (0.91–0.92)
Smoking (cigarettes per day)
< 10	1.14 (0.95–1.36)	1.41 (1.15–1.73)
10–20	0.70 (0.60–0.83)	0.79 (0.65–0.95)
> 20	1.54 (1.30–1.83)	1.74 (1.42–2.12)