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. 2019 Aug 27;28(12):1620–1628. doi: 10.1002/pds.4887

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© 2019 The Authors. Pharmacoepidemiology & Drug Safety Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Hazard ratio of DKA for new users of SGLT2 inhibitors versus comparator AHAs with censoring at the initiation of non‐index AHAs and discontinuation of the index AHA.

Abbreviations: AHA, antihyperglycemic agent; CCAE, IBM^® MarketScan^® Commercial Database; CI, confidence interval; DKA, diabetic ketoacidosis; DPP‐4, dipeptidyl peptidase‐4; GLP‐1, glucagon‐like peptide‐1; HR, hazard ratio; MDCD, IBM^® MarketScan^® Multi‐State Medicaid Database; MDCR, IBM^® MarketScan^® Medicare Supplemental Database; Optum, Optum^© De‐identified Clinformatics^® Data Mart Database; SGLT2, sodium glucose co‐transporter 2; SU, sulfonylurea; T2DM, type 2 diabetes mellitus; TZD, thiazolidinedione.

*Either no cases in the target and/or comparator cohort or number of cases were too few for the model to converge