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. Author manuscript; available in PMC: 2020 Nov 8.
Published in final edited form as: ACS Infect Dis. 2019 Oct 24;5(11):1915–1925. doi: 10.1021/acsinfecdis.9b00245

Table 3.

Isothermal titration calorimetry results

Compound Kd
(μM)
ΔH
(kcal mol−1)
−TΔS
(kcal mol−1)
N
9 1.66 ± 0.3 −4.33 ± 0.04 −3.55 ± 0.13 1.09 ± 0.06
8 13.8 ± 8.4 −1.61 ± 0.26 −5.09 ± 0.6 1.12 ± 0.05
16 1.19 ± 0.1 −4.11 ± 0.01 −1.88 ± 0.06 0.99 ± 0.06
15 38.7 ± 10.9 −2.76 ± 0.68 −1.23 ± 0.6 1.01 ± 0.07