Table 3.
Compound | Kd (μM) |
ΔH (kcal mol−1) |
−TΔS (kcal mol−1) |
N |
---|---|---|---|---|
9 | 1.66 ± 0.3 | −4.33 ± 0.04 | −3.55 ± 0.13 | 1.09 ± 0.06 |
8 | 13.8 ± 8.4 | −1.61 ± 0.26 | −5.09 ± 0.6 | 1.12 ± 0.05 |
16 | 1.19 ± 0.1 | −4.11 ± 0.01 | −1.88 ± 0.06 | 0.99 ± 0.06 |
15 | 38.7 ± 10.9 | −2.76 ± 0.68 | −1.23 ± 0.6 | 1.01 ± 0.07 |